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- CBD is an antioxidant, it helps to reduce absolutely free radicals in the body plus the harm they could cause to pores and skin cells.Cannabinoid R1 (CB1R) is a 60 kDa 7TM protein that belongs to the family of G protein-coupled receptors, course A. CB1R is expressed inside the central anxious process and upper GI tract, in contrast to CB2R that